Immunopharmacology
The functionality of the human immune system is based upon a network of feedback signals between the different leukocyte sub-populations as depicted only briefly in the picture. Each of the different cell types sends and reacts to a whole variety of messenger substances (mediators, cytokines).
Drugs (not only immuno-suppressors, but also ion-channel blockers, enzyme inhibitors, receptor antagonists, antibiotics or anti-viral compounds) can interfere with this regulatory network in a positive or negative manner, hereby changing the course of immune reactions sometimes dramatically.
Knowing such effects of newly developed drugs enables a precise definition, often even an extension, of their potential clinical applications.
Substances exhibiting doubtful effects may be eliminated from the R&D pipeline at an early stage or modified chemically to achieve the desired safety.
The test scheme "immuno-pharmacology" accelerate the substance development considerably.
Development of new drugs -
Improving the quality and speed of R&D by in vitro immunopharmacology
- EFFICIENT
- TIME SAVING
- COST SAVING
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